ER [FBbt_00007507]

Ring neuron that develops from the DALv2 neuroblast during the larval stage (Lovick et al., 2017; Omoto et al., 2018; Bridi et al., 2019). Its small soma is located in a cluster just dorsolateral to the antennal lobe and ventrolateral to the lateral accessory lobe (LAL) (Hanesch et al., 1989). There are approximately 150 R-neurons per hemisphere, making them more abundant than the extrinsic ring neurons (Omoto et al., 2018). They have projections that extend dorsoposteriorly, branching off localized neurites with postsynaptic terminals into the bulb or, less frequently, the LAL (Young and Armstrong, 2010; Omoto et al., 2018). They enter the lateral ellipsoid fascicle, and via a circular process, terminate medially into the ellipsoid body (EB) (Omoto et al., 2018). In the EB, distal neurites of R-neurons either project centrifugally (inside-out) or centripetally (outside-in) (Omoto et al., 2018) and have presynaptic terminals there (Young and Armstrong, 2010). They are GABAergic (Bridi et al., 2019). All subtypes have functions in regulating sleep (Yan et al., 2023).
Tags:
ER ER ER ER

ER

ID: FBbt_00007507

Adult GABAergic lineage EBa1 DALv2 secondary neuron

Ring neuron that develops from the DALv2 neuroblast during the larval stage (Lovick et al., 2017; Omoto et al., 2018; Bridi et al., 2019). Its small soma is located in a cluster just dorsolateral to the antennal lobe and ventrolateral to the lateral accessory lobe (LAL) (Hanesch et al., 1989). There are approximately 150 R-neurons per hemisphere, making them more abundant than the extrinsic ring neurons (Omoto et al., 2018). They have projections that extend dorsoposteriorly, branching off localized neurites with postsynaptic terminals into the bulb or, less frequently, the LAL (Young and Armstrong, 2010; Omoto et al., 2018). They enter the lateral ellipsoid fascicle, and via a circular process, terminate medially into the ellipsoid body (EB) (Omoto et al., 2018). In the EB, distal neurites of R-neurons either project centrifugally (inside-out) or centripetally (outside-in) (Omoto et al., 2018) and have presynaptic terminals there (Young and Armstrong, 2010). They are GABAergic (Bridi et al., 2019). All subtypes have functions in regulating sleep (Yan et al., 2023).

Sites inferred to be presynaptic by localization of fluorescently tagged synaptobrevin and to be postsynaptic by localization of fluorescently tagged DSCAM (Young and Armstrong, 2010).

Open in VFB 3D Browser →
## Classification

Relationships

Alternative Names

Synonym Scope Reference
dorsal cluster Poxn-neuron related synonym Minocha et al., 2017
R neuron exact synonym Renn et al., 1999
R-neuron exact synonym Hanesch et al., 1989
R-cell exact synonym Hanesch et al., 1989
LTR-EB exact synonym Young and Armstrong, 2010
ER exact synonym Scheffer et al., 2020
ER-neuron exact synonym Kandimalla et al., 2023
DC Poxn-neuron related synonym Minocha et al., 2017
ring neuron R exact synonym